To ensure product quality and safety for users, the production process must strictly comply with GMP (Good Manufacturing Practices) standards. So what is a GMP-standard hard capsule production line? Let's find out more in the article below with Intech Group.

Concept and characteristics of hard capsules in the production line

Hard capsules are one of the popular dosage forms in the pharmaceutical and functional food industry, widely produced on modern hard capsule production lines. Hard capsules consist of two main parts: the capsule body and the capsule cap, usually made from gelatin or polymers of plant origin, used to contain active ingredients in the form of powder, granules or small pellets.
Some outstanding features of hard capsules:

• Conceals the unpleasant taste of the drug inside

• Easy to swallow thanks to the smooth, user-friendly design

• Supports accurate dosage, increasing treatment effectiveness

• High stability during storage and transportation

• Quick solubility in physiological environment, helping to release active ingredients effectively

The above advantages make the GMP-standard hard capsule production line increasingly widely used in pharmaceutical and health food factories.

What is a GMP-certified hard capsule production line?

A GMP-certified hard capsule production line (Good Manufacturing Practice) is a production system designed and operated according to strict standards to ensure the quality, safety and stability of pharmaceutical products and health food products. This is a mandatory requirement for manufacturing facilities that want to bring products to domestic and foreign markets.

- Factory design: Must meet hygiene requirements, be reasonably zoned to prevent cross-contamination and control the environment such as temperature, humidity, air pressure and light.

- Equipment and machinery: Made of non-contaminating materials, easy to clean, periodically maintained and accurately calibrated to ensure stable performance.

- Input materials: Must have clear origin, be tested for quality before use and stored under proper conditions.

- Production process: Standardized for each stage, with specific operating instructions, fully recorded to trace the origin when necessary.

- Personnel: The operation and quality control team must be thoroughly trained in GMP, personal hygiene and production safety.

- Quality control system: Includes periodic inspection of raw materials, semi-finished products and final products to ensure that the product meets the prescribed standards.

Establishing a GMP-standard hard capsule production line helps businesses improve product quality, which is also a prerequisite for obtaining a production license and expanding the distribution market.

Machinery in GMP standard hard capsule production line

To ensure the quality and safety of hard capsule products, GMP standard hard capsule production line needs to be equipped with modern equipment. Below are the main machines that are indispensable in the production system:

- Fluidized bed spray dryer and granulator: Helps dry powder or granule materials, while creating even granules, achieving ideal humidity to ensure product stability in capsules.

- Automatic capsule filling machine: An important device of the production line, this machine quantifies and fills raw materials into capsule shells with high precision, helping capsules have uniform mass and stable active ingredient content.

- Curved conveyor, drying conveyor: Curved conveyor helps flexibly connect between devices, supporting the transportation of raw materials and finished products through stages smoothly, saving space and improving efficiency. Drying conveyor is used in the drying stage of raw materials or semi-finished products when granulating before filling capsules or pressing tablets.

- Bottling machine: After completing the capsule filling, the product is put into the jar and sealed with a protective film. This helps to ensure that the capsules are protected from the effects of humidity, light and air during storage and transportation.

- Automatic blister packing machine: For products requiring blister packaging, the blister packing machine helps to create sturdy packaging, ensuring that the capsules are not broken or deformed, while increasing aesthetics and convenience for users.

- Packing machine, loading and unloading system: The packing machine has the function of packing jars or blisters of capsules into cartons. After packaging, the product cartons will be automatically loaded onto pallets by the loading robot, preparing for storage or transportation.

With many years of experience in the field of production automation, Intech Group is proud to be a pioneer in providing GMP-standard hard capsule production lines in Vietnam. We are committed to providing businesses with comprehensive production solutions from consulting, design, installation to maintenance to help improve productivity, control quality and strictly comply with standards in the pharmaceutical and food industries. Contact us today for advice and support via Hotline: 0966.966.032 - 0983.113.